Sildenafil Actavis 100 Mg Film-coated Tablets

In addition, the frequency of medically important adverse reactions reported from post-marketing experience is included as not known. Renal insufficiency. Stronger CYP3A4 inhibitors such as ketoconazole and itraconazole would be expected to have greater effects. Sildenafil Actavis is not indicated for individuals below 18 years of age. Common may affect up to 1 in 10 people: If you have any 100mg questions, ask your doctor, pharmacist or nurse. Sldenafil double-blind, placebo-controlled exercise stress trial evaluated patients with erectile dysfunction and chronic stable angina who regularly received anti-anginal medicinal products except nitrates. Legal Category POM: To bookmark a medicine you must sign up and log in. Reactions such as pain, tingling, or numbness of the face, neck, chest, or jaw are also considered serious actavis effects 100mt cause to seek emergency medical attention, as is a prolonged erection lasting sildenafil than 4 hours priapism. The actavs commonly reported adverse reactions in 100mg studies among sildenafil treated patients were headache, flushing, dyspepsia, nasal congestion, actavis, nausea, hot flush, visual disturbance, cyanopsia and vision blurred. If you actavis taking medicines known as protease inhibitors, such as for the treatment 100mg HIV, your doctor may start you on the lowest dose 25 mg of Sildenafil Actavis. Concomitant use with other treatments for erectile dysfunction. Based on efficacy and tolerability, the dose may be increased step-wise to 50 mg up to mg sildenafil necessary. This site uses cookies. For any information about this medicine, please contact the local representative of the Marketing Authorisation Holder:. SlovenijaSanolabor d. Sildenafil Actavis 50 mg film-coated tablets are blue elliptical, biconvex, You can report side effects to your sildenafil, or directly at www.

Children and adolescents Sildenafil Actavis should not be given to individuals under the age of In vivo studies. You can read more about the scheduling of medicines as well as the different scheduling categories on our Scheduling of medicines and 100mg information page. Sildenafil Actavis can cause dizziness and can affect vision. This information is intended for use by health professionals. Sildenafil Actavis mg film-coated tablets are blue elliptical, biconvex, Find out more here. The active ingredient in Sildenafil Actavis, sildenafil, belongs to a group of medicines called phosphodiesterase type 5 Actavis inhibitors. What benefits has it shown during the studies? Further information on clinical trials In clinical 100mg sildenafil was administered to more than patients aged Qualitative and quantitative composition 3. This is consistent with ritonavir's marked effects on a broad range of P substrates. Two clinical studies were specifically designed to assess the time window sildenafil dosing during which sildenafil could produce an erection in response to sexual stimulation, sildenafil actavis 100mg. This medicine has been prescribed for you only. Contact your doctor if you take more tablets than you should. Its effect is more potent on PDE5 than on other known phosphodiesterases. Uncommon may affect up to 1 in people: Therefore sildenafil should be administered to these patients only after careful benefit-risk assessment. Pooling of the following classes of antihypertensive medication: Sign Up Log In Cancel. Distribution Actavis mean steady state volume of distribution V d for sildenafil is l, indicating distribution into the tissues.

Continue typing to refine. In order to minimise the potential for developing postural actais, actavis should be hemodynamically stable on alpha-blocker therapy prior to initiating sildenafil actais. In clinical trials sildenafil was administered to more than patients aged Toggle navigation. Sildenafil mg did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates. Therefore the use of such combinations is not recommended. For actavis use. The mean maximum decreases in supine systolic blood pressure following mg oral dosing of sildenafil was 100mg. Patients with hepatic impairment. Effects on axtavis. Special populations. Women Sildenafil Actavis is not indicated for use by women. Men experiencing erectile dysfunction should speak to 100mg doctor to determine the cause. Tabulated list of adverse reactions. Sildenafil Actavis contains the active substance sildenafil which belongs to a group sildenafil medicines called phosphodiesterase type 5 PDE5 inhibitors. Who should take sildenafil? Sildenafil Actavis mg film-coated tablets are blue elliptical, biconvex, Sildenafil Actavis mg film-coated tablets. After oral dosing of sildenafil AUC and C max increase in proportion with dose over the recommended dose range mg. Show table of contents Hide table of contents 1. Marketing sildeenafil number s 9. Concomitant use with sildenafil treatments for erectile dysfunction The safety and efficacy of combinations of sildenafil with other treatments for erectile dysfunction have not been studied. Co-administration of sildenafil with atavis is not advised see section 4. If you have been told by your doctor that you have an intolerance to some sugars, such as lactose, contact your doctor before taking Sildenafil Actavis.

This medicine is available from a pharmacist and requires a prescription. Please tell your doctor or pharmacist if you are taking or have recently taken other medicines, including medicines obtained 100mg prescription. During normal sexual stimulation, cGMP is sildenafil in the penis, where it actavis the muscle in the spongy tissue of the penis the corpora cavernosa to relax. Sildenafil Actavis sildenafil film-coated tablet, 4 Sildenafil Actavis 50 mg film-coated tablet, 4. Company contact details Accord-UK Ltd. The pharmacokinetics of sildenafil in patients with severely impaired hepatic function have not been studied. Initiation of sildenafil at a dose of 25 mg should be considered see section 4. The following groups were not well represented or excluded from clinical trials: Studies aactavis vitro have shown that sildenafil is selective for PDE5, which is involved in the erection process. Get in a semi-sitting position and try to relax. Sildenafil has no direct relaxant effect on isolated human actavia cavernosum but potently enhances the relaxant effect of NO on this tissue. Summary of the safety profile The safety profile of sildenafil is based on 8, patients who received the recommended dosing regimen in 100mg placebo-controlled clinical studies. In a specific interaction study, where sildenafil mg was co-administered with amlodipine in hypertensive patients, there was an additional reduction on supine systolic blood pressure of 8 mmHg. Special considerations for patients with kidney or liver problems You should tell your doctor if you have kidney or liver problems. Actavis to prescribing sildenafil, physicians should carefully consider whether their patients with certain underlying conditions could be adversely affected by such vasodilatory effects, especially in combination with sexual activity, sildenafil actavis 100mg. Take special actavi with Sildenafil Actavis Tell your doctor If you have sickle cell anaemia an abnormality of red blood cellsleukaemia cancer of blood cellsmultiple myeloma cancer of bone marrow.

Sildenafil actavis 100mg

Your doctor may decide on a lower dose for you. Sildeenafil tablet contains Sildenafil Actavis should not be administered to men with rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Why has it been approved? These additional blood pressure reductions were of a sildenavil magnitude to those seen when sildenafil was administered alone to sldenafil volunteers see section 5. Swallow the tablet whole with a glass of water. The N-desmethyl metabolite is zildenafil metabolised, with a terminal half-life of approximately 4 silednafil. The active ingredient in Sildenafil Actavis, sildenafil, belongs to a actavis of sildenafil called phosphodiesterase type 5 PDE5 inhibitors. Based on these pharmacokinetic results co-administration of sildenafil with ritonavir is not advised see section 4. The safety of sildenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated: Renal dialysis is 100mg expected to accelerate clearance as sildenafil is highly bound to plasma proteins and not eliminated in the urine. Nicorandil is a hybrid of potassium channel activator and nitrate, sildenafil actavis 100mg. Clinical particulars 4. It is considered a low toxicity drug and sidlenafil generally well tolerated by most men. Uncommon side effects include: After around 24 hours none of the active ingredient remains in the bodies plasma. Most, but not all, of these men had heart problems before taking this medicine. Concomitant use with alpha-blockers Caution is advised when sildenafil is administered to patients taking an alpha-blocker, as the co-administration may lead to symptomatic hypotension in a few susceptible individuals see section 4. It is not possible to determine whether these events are related directly to these factors or to other factors. To bookmark a medicine you must sign up and log in. Sildenafil has no effect on visual acuity or contrast sensitivity. If you experience any of the following serious side xctavis stop taking Sildenafil Actavis and seek medical help immediately:. Because Sildenafil Actavis is a generic medicine, studies have been limited to tests to determine that it is bioequivalent to the reference medicine, Viagra.

You should not take Sildenafil Actavis if you are a woman. After around 24 hours none of the active ingredient remains in the bodies plasma. Sildenafil Actavis mg tablets Each tablet contains 100mg oral doses of sildenafil up to mg in healthy volunteers produced no clinically relevant effects on ECG. Pooling of the following classes of antihypertensive medication: This is most likely to occur within 4 hours post sildenafil dosing see sections sildenafil. Below is a text only representation of the Patient Information Leaflet. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk. Most, but not all, of these patients had pre-existing cardiovascular risk factors. This is when a man cannot actavis, or keep a hard, erect penis suitable for sexual activity. There is a fold selectivity over PDE6 which is involved in the 100mb pathway in the retina. Is this medicine subsidised? Tablet core: You should take Sildenafil Actavis about one actagis before sexual activity. Sildenafil Actavis is not indicated for use by women. The maximum recommended dose is mg. If you experience sudden decrease or loss of vision, stop taking Sildenafil Actavis and contact your doctor immediately.

Concomitant use with ritonavir. Sildenafil Actavis mg film-coated tablets. Your email: Therefore sexual stimulation is required catavis order for sildenafil to produce its intended beneficial pharmacological effects. Hypersensitivity to aactavis active substance or to any of the excipients sildenafil in section 6. Doses of mg did not result in increased efficacy but the incidence of adverse reactions headache, flushing, dizziness, dyspepsia, nasal congestion, altered vision was increased. Actavis Group PTC actavia. If you have been told by your doctor that actavis have an intolerance to some sugars, such as lactose, contact your doctor before taking Sildenafil Actavis, sildenafil actavis 100mg. In particular, sildenafil sildenaifl greater than 4,fold selectivity for PDE5 over PDE3, the cAMP-specific phosphodiesterase isoform involved in the control of cardiac sildenafil. Table 1: Drinking alcohol can temporarily impair the ability to get an erection. The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Studies with human platelets indicate that sildenafil potentiates the antiaggregatory effect of sodium nitroprusside in vitro. Prior to initiating 100mg treatment for erectile dysfunction, physicians should consider the cardiovascular status of their patients, since 100mg is a degree of cardiac risk associated with actavis activity. Serious cardiovascular events, including myocardial infarction, unstable angina, sudden slldenafil death, ventricular arrhythmia, cerebrovascular haemorrhage, transient ischaemic attack, hypertension and hypotension have been reported post-marketing in temporal association with the use of sildenafil. Taking Sildenafil Actavis with food and drink Sildenafil Actavis can be taken with or without food.

Sildenafil had no effect on ritonavir pharmacokinetics. You should contact your doctor immediately if you experience any of the following symptoms after taking this medicinal product: Uncommon side effects include: To view the changes to a medicine you must sign up and log in. See 4. Stronger CYP3A4 inhibitors such as ketoconazole and itraconazole would be expected to have greater effects. As soon as a potential patient thinks of taking medicine for erectile dysfunction the practical questions come into play: If you are not certain, ask your doctor or pharmacist. Do not use nitrates to treat your chest pain. This is most likely to occur within 4 hours post sildenafil dosing. A medical history and physical examination should be undertaken to diagnose erectile dysfunction and determine potential underlying causes, before pharmacological treatment is considered. You should not take Sildenafil Actavis if you do not have erectile dysfunction. The results demonstrated no clinically relevant differences between sildenafil and placebo in time to limiting angina. Cases of visual defects have been reported spontaneously in connection with the intake of sildenafil and other PDE5 inhibitors see section 4. Pharmacotherapeutic group: Tabulated list of adverse reactions. A double-blind, placebo-controlled exercise stress trial evaluated patients with erectile dysfunction and chronic stable angina who regularly received anti-anginal medicinal products except nitrates. This means that Sildenafil Actavis is similar to a? Clinical particulars 4. In the natural setting, i. Effects of other medicinal products on sildenafil In vitro studies Sildenafil metabolism is principally mediated by the cytochrome P CYP isoforms 3A4 major route and 2C9 minor route.

sildenafil actavis 100mg

You should not take Sildenafil Actavis more than once a day. Based on efficacy and tolerability, the dose may be increased step-wise to 50 mg up to mg as necessary. Pooling of the following classes of antihypertensive medication: In particular, sildenafil has greater than 4,fold selectivity for PDE5 over PDE3, the cAMP-specific phosphodiesterase isoform involved in the control of cardiac contractility. Single oral doses of sildenafil up to mg in healthy volunteers produced no clinically relevant effects on ECG. If you have certain rare inherited eye diseases such as retinitis pigmentosa. Sildenafil Actavis is not indicated for individuals below 18 years of age. Sildenafil is an oral therapy for erectile dysfunction. Company contact details Accord-UK Ltd. In healthy male volunteers, sildenafil at steady state 80 mg t. Prior to prescribing sildenafil, physicians should carefully consider whether their patients with certain underlying conditions could be adversely affected by such vasodilatory effects, especially in combination with sexual activity. Prescription only medicine. There are no data on the interaction of sildenafil and non-specific phosphodiesterase inhibitors such as theophylline or dipyridamole. If priapism is not treated immediately, penile tissue damage and permanent loss of potency could result. Please enter your name Please enter your email Your email is invalid. To reduce the chance that these symptoms might happen, you should be on a regular daily dose of your alpha-blocker before you start Sildenafil Actavis. What is it used for? This means that Sildenafil Actavis is similar to a? Special populations. If you have any further questions on the use of this product, ask your doctor or pharmacist. Co-administration of sildenafil with ritonavir is not advised see section 4. Common may affect up to 1 in 10 people: The amount of time Sildenafil Actavis takes slidenafil work varies from person to person, but it normally takes between half actavis hour sildenafil one hour. How should it be stored? Sildemafil in special patient groups. Preclinical studies showed additive systemic blood pressure lowering effect when PDE5 inhibitors were combined 100mg riociguat. The physiological mechanism responsible for erection of the penis involves the release of nitric oxide NO in the corpus cavernosum during sexual stimulation.

To email a medicine you must sign up and log in. Within each frequency grouping, undesirable effects are presented in order of decreasing seriousness. If you get any side effects, talk to you doctor or pharmacist or nurse. If taken without food the maximum drug concentration in the blood is shown at 1 hour post-dose. Name of the medicinal product 2. Clinical particulars 4. Active ingredient sildenafil citrate. Pharmacological properties 5. The European Medicines Agency has waived the obligation to submit the results of studies with the reference medicinal product containing sildenafil in all subsets of the paediatric population for the treatment of erectile dysfunction. Prior to prescribing sildenafil, physicians should carefully consider whether their patients with certain underlying conditions could be adversely affected by such vasodilatory effects, especially in combination with sexual activity. Further information on clinical trials. You should be aware of how you react to Sildenafil Actavis before you drive or use machinery. A sudden decrease or loss of vision - this occurs rarely Serious skin reactions - this occurs rarely Symptoms may include severe peeling and swelling of the skin, blistering of the mouth, genitals and around the eyes, fever. Doses above mg do not increase the efficacy. Respiratory, thoracic and mediastinal disorders. Stronger CYP3A4 inhibitors such as ketoconazole and itraconazole would be expected to have greater effects. The maximum recommended dosing frequency is once per day. Company contact details Accord-UK Ltd. You should not use Actvais Actavis with any other oral or local treatments for erectile dysfunction. Sildenafil Actavis mg film-coated tablets are blue elliptical, biconvex, Date of revision of the text. Sign Up Log In Cancel. Patients with increased susceptibility to vasodilators include those with left ventricular outflow obstruction e. Hepatic insufficiency. Two clinical studies were specifically designed to assess the time window after dosing during which sildenafil could produce an erection in response to sexual stimulation.